Growing up, Muggshot was often bullied and his only source of happiness came from watching old gangster movies. Because of his upbringing, he decided to become a gangster to get revenge. For the remainder of his childhood and teen years, he spent his days lifting weights until his arms became so massive, he ended walking like an ape because he neglected his legs. He beat up his tormenters and found a criminal empire and eventually was recruited into the Fiendish Five. After helping the evil Clockwerk kill Sly's father, Muggshot fled to Mesa City with a piece of the Thievius Raccoonus.
Sly encountered Muggshot and demanded the piece of the Thievius Raccoonus, angered that Sly messed up his operations. Sly was unable to harm Muggshot physically and had to hide behind crystals to avoid being hit. Sly was able to defeat him by redirecting sunlight at the crystals to fry the dog. Sly took the piece of the Thievius Raccoonus while Muggshot was arrested by Carmelita.
In Sly 3 Muggshot, now redesigned with longer legs, took part in the ACES competition. To win the competition, Sly and the gang lured Carmelita to his location where she fought against him and was able to defeat him with her laser guns.